A "bold move": The story of the first spruce genome
About fifteen years ago, scientists at SciLifeLab and Umeå Plant Science Center teamed up to tackle a "super hard technical challenge" – sequencing the enormous spruce genome that is about seven times the size of the human genome.
The original paper, published in Nature in 2013, has been cited almost 1500 times. Ten years ago, a clone of the original spruce was planted in the the Uppsala Botanical Gardens.
High-impact planetary biology projects selected for further development
Researchers across Sweden submitted 17 strong proposals to the SciLifeLab Planetary Biology strategic area.
After a evaluation process, five projects have been selected to move forward to dedicated brainstorming workshops aimed at maximizing their scientific and societal impact.
From infrastructure to innovation: SciLifeLab Lund Day highlights collaboration
Researchers, technology platforms, and strategic research initiatives gathered in Lund to exchange ideas, collaborate and learn about what SciLifeLab has to offer.
“A key outcome was the dialogue we fostered with the Strategic Research Areas at Lund University,” says Site Coordinator Anabella Aguilera.
Breast cancer risk differs between types of hormonal contraceptives
SciLifeLab and Uppsala University researchers show that the risk of breast cancer varies between different types of hormonal contraceptives.
More than two million women and girls aged 13–49 across Sweden were followed between 2006 and 2019, using national health registers to compare how different hormonal methods influence cancer risk over time.
Pictured:
Senior author Åsa Johansson and first author Fatemeh Hadizadeh.
SciLifeLab researchers awarded competitive starting grants in medicine and health
DDLS Fellows Antonio Lentini (Linköping University) and Arian Lundberg (KTH Royal Institute of Technology) have both been awarded Swedish Research Council starting grants in medicine and health.
31 out of 262 applications were funded, corresponding to a success rate of 12 percent. The grants support promising early-career researchers in establishing independent research groups and advancing innovative medical research in Sweden.
DDD exit project explores new treatment strategies for cancer and lupus
A Drug Discovery and Development (DDD) Platform exit project at SciLifeLab has followed the scientific journey of an established antiparasitic drug towards new potential applications in cancer and autoimmune diseases.
The project, led by Peter Nygren, Mårten Fryknäs, and Rolf Larsson at Uppsala University, originated from an unexpected observation that the antiparasitic drug mebendazole showed effects in cancer models.
Heart ‘blueprint’ made openly available in unique resource
A detailed map of the developing human heart, showing how different groups of cells are arranged and how they interact in fetal heart development have been published by SciLifeLab and KTH Royal Institute of Technology researchers Joakim Lundeberg, Raphaël Mauron and Enikő Lázár.
Breast cancer risk differs between types of hormonal contraceptives
The study from Åsa Johansson and Fatemeh Hadizadeh featured above, that investigates breast cancer risk in relation to differerent types of hormonal contraceptives, has attracted media attention.
Life Science Sweden: Nytt svenskt alzheimerläkemedel i fas III – ”Vi angriper det största problemet”
En ny typ av alzheimerbehandling är på väg att utvecklas av svenska forskare.
”Det här lät först för bra för att vara sant, men efter tio års arbete har vi vant oss vid tanken”, säger KTH-professorn och serieentreprenören [och SciLifeLab Group Leader] Mathias Uhlén.
Kvalitetsmagasinet: Han bygger AI som ska eliminera djurförsök och snabba upp läkemedelsutvecklingen
Robotiserade labb banar väg för säkrare läkemedel och en framtid utan djurförsök, något som professor Ola Spjuth vid Uppsala universitet [och SciLifeLab AI Lead] redan gör till verklighet.
– Vi accelererar läkemedelsutvecklingen, säger han.
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